Early reactions
|
Skin | Erythema | 8.8 | [6.9; 11.6] | Turesson and Thames (1989)
|
Erythema | 12.3 | [1.8; 22.8] | Bentzen et al. (1988)
|
Dry desquamation | ~8 | N/A | Chogule and Supe (1993)
|
Desquamation | 11.2 | [8.5; 17.6] | Turesson and Thames (1989)
|
Oral mucosa | Mucositis | 9.3 | [5.8; 17.9] | Denham et al. (1995)
|
Mucositis | 15 | [-15; 45] | Rezvani et al. (1991)
|
Mucositis | 8 | N/A | Chogule and Supe (1993)
|
Late reactions
|
Skin/vasculature | Telangiectasia | 2.8 | [1.7; 3.8] | Turesson and Thames (1989)
|
Telangiectasia | 2.6 | [2.2; 3.3] | Bentzen et al. (1990)
|
Telangiectasia | 2.8 | [-0.1; 8.1] | Bentzen and Overgaard (1991)
|
Telangiectasia | 3.8 | [1.8; 5.7] | Haviland et al. (2013)
|
Subcutis | Fibrosis | 1.7 | [0.6; 2.6] | Bentzen and Overgaard (1991)
|
Breast | Cosmetic change in appearance | 3.5 | [0.7; 6.4] | Haviland et al. (2013)
|
Induration (fibrosis) | 4.0 | [2.3; 5.6] | Haviland et al. (2013)
|
Breast oedema | 4.7 | [2.4; 7.0] | Haviland et al. (2013)
|
Muscle/vasculature/cartilage | Impaired shoulder movement | 3.5 | [0.7; 6.2] | Bentzen et al. (1989)
|
Nerve | Brachial plexopathy | <3.5a | N/A | Olsen et al. (1990)
|
Brachial plexopathy | ~2 | N/A | Powell et al. (1990)
|
Optic neuropathy | 1.6 | [-7; 10] | Jiang et al. (1994)
|
Spinal cord | Myelopathy | <3.3 | N/A | Dische et al. (1981)
|
Eye | Corneal injury | 2.9 | [-4; 10] | Jiang et al. (1994)
|
Bowel | Stricture/perforation | 3.9 | [2.5; 5.3] | Deore et al. (1993)
|
Bowel | Various late effects | 4.3 | [2.2; 9.6] | Dische et al. (1999)
|
Lung | Pneumonitis | 4.0 | [2.2; 5.8] | Bentzen et al. (2000)
|
Lung fibrosis (radiological) | 3.1 | [-0.2; 8.5] | Dubray et al. (1995)
|
Head and neck | Various late effects | 3.5 | [1.1; 5.9] | Rezvani et al. (1991)
|
Various late effects | 4.0 | [3.3; 5.0] | Stuschke and Thames (1999)
|
Supraglottic larynx | Various late effects | 3.8 | [0.8; 14] | Maciejewski et al. (1986)
|
Oral cavity+oropharynx | Various late effects | 0.8 | [-0.6; 2.5] | Maciejewski et al. (1990)
|
Tumours
|
Head and neck | | | |
|
Various | | 10.5 | [6.5; 29] | Stuschke and Thames (1999)
|
Larynx | | 14.5a | [4.9; 24] | Rezvani et al. (1993)
|
Vocal cord | | ~13 | ‘wide’ | Robertson et al. (1993)
|
Buccal mucosa | | 6.6 | [2.9; ∞] | Maciejewski et al. (1989)
|
Tonsil | | 7.2 | [3.6; ∞] | Maciejewski et al. (1989)
|
Nasopharynx | | 16 | [-11; 43] | Lee et al. (1995)
|
Lung (NSCLC, early) | | 8.2 | [7.0; 9.4] | Stuschke and Pöttgen (2010)
|
Skin | | 8.5a | [4.5; 11.3] | Trott et al. (1984)
|
Prostateb | | 2.7 | [1.6; 3.8] | Vogelius and Bentzen (2018)
|
Breast | | 3.5 | [1.2; 5.7] | Haviland et al. (2013)
|
Oesophagus | | 4.9 | [1.5; 17] | Geh et al. (2006)
|
Melanoma | | 0.6 | [-1.1; 2.5] | Bentzen et al. (1989)
|
Liposarcoma | | 0.4 | [-1.4; 5.4] | Thames and Suit (1986)
|